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Epidermal growth factor receptor expression and signaling are essential in glutamine's cytoprotective mechanism in heat-stressed intestinal epithelial-6 cells

Epidermal growth factor receptor (EGFR) expression and signaling can induce cellular protection after intestinal inflammation. l-Glutamine (GLN) is known to prevent apoptosis after intestinal injury by activating MAPK and phosphatidylinositol 3-kinase (PI3-K)/Akt pathways. However, the role of EGFR...

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Autors principals: Niederlechner, Stefanie, Baird, Christine, Petrie, Benjamin, Wischmeyer, Erhard, Wischmeyer, Paul E.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602678/
https://ncbi.nlm.nih.gov/pubmed/23275616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00418.2012
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