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Metabolic programming effects initiated in the suckling period predisposing for adult-onset obesity cannot be reversed by calorie restriction

Neonatal rats reared on high-carbohydrate (HC) milk formula developed chronic hyperinsulinemia and adult-onset obesity due to programming of islets and the hypothalamic energy circuitry. In this study, calorie restriction by pair-feeding was imposed on HC male rats (HC/PF) to normalize food intake s...

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書誌詳細
主要な著者: Srinivasan, Malathi, Mahmood, Saleh, Patel, Mulchand S.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602662/
https://ncbi.nlm.nih.gov/pubmed/23249696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00519.2012
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