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Isolation of rsp-1, a novel cDNA capable of suppressing v-Ras transformation.

Using an expression cloning assay, we have isolated a novel cDNA, referred to as rsp-1, which suppresses the v-Ras-transformed phenotype. When introduced into NIH 3T3 fibroblasts under the control of a metallothionein promoter, rsp-1 confers resistance to v-Ras, but not to v-Mos or v-Src, and inhibi...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Cutler, M L, Bassin, R H, Zanoni, L, Talbot, N
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360236/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1508180/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.9.3750
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