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mTOR complex 2 is involved in regulation of Cbl-dependent c-FLIP degradation and sensitivity of TRAIL-induced apoptosis

The mammalian target of rapamycin (mTOR) positively regulates cell proliferation and survival through forming two complexes with raptor (mTOR complex 1; mTORC1) or rictor (mTOR complex 2; mTORC2). Compared with the mTORC1, relatively little is known about the biological functions of mTORC2. The curr...

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Bibliografske podrobnosti
Main Authors: Zhao, Liqun, Yue, Ping, Khuri, Fadlo R., Sun, Shi-Yong
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602308/
https://ncbi.nlm.nih.gov/pubmed/23319802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3710
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