Reduced IL-10 Production in Fetal Type II Epithelial Cells Exposed to Mechanical Stretch Is Mediated via Activation of IL-6-SOCS3 Signaling Pathway

An imbalance between pro-inflammatory and anti-inflammatory cytokines is a key factor in the lung injury of premature infants exposed to mechanical ventilation. Previous studies have shown that lung cells exposed to stretch produces reduced amounts of the anti-inflammatory cytokine IL-10. The object...

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Main Authors: Hokenson, Michael A., Wang, Yulian, Hawwa, Renda L., Huang, Zheping, Sharma, Surendra, Sanchez-Esteban, Juan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602195/
https://ncbi.nlm.nih.gov/pubmed/23527226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059598
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