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Rhesus Macaque Lymph Node PD-1(hi)CD4(+) T Cells Express High Levels of CXCR5 and IL-21 and Display a CCR7(lo)ICOS(+)Bcl6(+) T-Follicular Helper (Tfh) Cell Phenotype
CD4 T follicular helper (Tfh) cells play a unique and essential role in the generation of B cell responses in the lymph node microenvironment. Here we sought to determine if differential expression of PD-1 could be used to delineate Tfh cells in rhesus macaque lymph nodes (LN). CD3(+)CD4(+) T cells...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3602102/ https://ncbi.nlm.nih.gov/pubmed/23527264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059758 |
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