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Comparative analysis of the transduction efficiency of five adeno associated virus serotypes and VSV-G pseudotype lentiviral vector in lung cancer cells

BACKGROUND: Lung cancer is the leading cause of cancer-related deaths in the US. Recombinant vectors based on adeno-associated virus (AAV) and lentivirus are promising delivery tools for gene therapy due to low toxicity and long term expression. The efficiency of the gene delivery system is one of t...

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Autori principali: Chen, Chiachen, Akerstrom, Victoria, Baus, James, Lan, Michael S, Breslin, Mary B
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602085/
https://ncbi.nlm.nih.gov/pubmed/23497017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-86
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