Transgenic expression of COL1A1-chloramphenicol acetyltransferase fusion genes in bone: differential utilization of promoter elements in vivo and in cultured cells.

To directly compare the patterns of collagen promoter expression in cells and tissues, the activity of COL1A1 fusion genes in calvariae of neonatal transgenic mice and in primary bone cell cultures derived by sequential digestion of transgenic calvariae was measured. ColCAT3.6 contains 3.6 kb (posit...

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Détails bibliographiques
Auteurs principaux: Krebsbach, P H, Harrison, J R, Lichtler, A C, Woody, C O, Rowe, D W, Kream, B E
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC360205/
https://ncbi.nlm.nih.gov/pubmed/8355676
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