TRPV1, but not TRPA1, in primary sensory neurons contributes to cutaneous incision-mediated hypersensitivity

BACKGROUND: Mechanisms underlying postoperative pain remain poorly understood. In rodents, skin-only incisions induce mechanical and heat hypersensitivity similar to levels observed with skin plus deep incisions. Therefore, cutaneous injury might drive the majority of postoperative pain. TRPA1 and T...

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Bibliographic Details
Main Authors: Barabas, Marie E, Stucky, Cheryl L
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602024/
https://ncbi.nlm.nih.gov/pubmed/23497345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-9-9
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