Nedd8 processing enzymes in Schizosaccharomyces pombe

BACKGROUND: Conjugation of the ubiquitin-like modifier Nedd8 to cullins is critical for the function of SCF-type ubiquitin ligases and thus facilitates ubiquitin conjugation and ultimately degradation of SCF substrates, including several cell cycle regulators. Like ubiquitin, Nedd8 is produced as a...

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Bibliographic Details
Main Authors: O’Donoghue, Jean E, Bech-Otschir, Dawadschargal, Larsen, Ida B, Wallace, Mairi, Hartmann-Petersen, Rasmus, Gordon, Colin
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602023/
https://ncbi.nlm.nih.gov/pubmed/23496905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-14-8
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