Decrease of survivin, p53 and Bcl-2 expression in chemorefractory colorectal liver metastases may be predictive of radiosensivity after radioembolization with yttrium-90 resin microspheres

In a prospective multicenter phase II trial of radioembolization with yttrium-90 ((90)Y-RE) in chemorefractory liver-dominant metastatic colorectal cancer (mCRC), we showed that median survival was 12.6 months (95% CI 7.0–18.3) with 48% of 50 patients achieving disease control. In this extension ret...

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Detalhes bibliográficos
Main Authors: Melucci, Elisa, Cosimelli, Maurizio, Carpanese, Livio, Pizzi, Giuseppe, Izzo, Francesco, Fiore, Francesco, Golfieri, Rita, Giampalma, Emanuela, Sperduti, Isabella, Ercolani, Cristiana, Sciuto, Rosa, Mancini, Raffaello, Garufi, Carlo, Diodoro, Maria Grazia, Mottolese, Marcella
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602019/
https://ncbi.nlm.nih.gov/pubmed/23497522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-32-13
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