Serotonin promotes the proliferation of serum-deprived hepatocellular carcinoma cells via upregulation of FOXO3a

BACKGROUND: Peripheral serotonin is involved in tumorigenesis and induces a pro-proliferative effect in hepatocellular carcinoma (HCC) cells; however, the intracellular mechanisms by which serotonin exerts a mitogenic effect remain unclear. In this research, we examined whether FOXO3a, a transcripti...

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Bibliografiske detaljer
Main Authors: Liang, Chao, Chen, Wei, Zhi, Xiao, Ma, Tao, Xia, Xuefeng, Liu, Hao, Zhang, Qi, Hu, Qida, Zhang, Yun, Bai, Xueli, Liang, Tingbo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601970/
https://ncbi.nlm.nih.gov/pubmed/23418729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-14
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