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Number of Patients Studied Prior to Approval of New Medicines: A Database Analysis

BACKGROUND: At the time of approval of a new medicine, there are few long-term data on the medicine's benefit–risk balance. Clinical trials are designed to demonstrate efficacy, but have major limitations with regard to safety in terms of patient exposure and length of follow-up. This study of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Duijnhoven, Ruben G., Straus, Sabine M. J. M., Raine, June M., de Boer, Anthonius, Hoes, Arno W., De Bruin, Marie L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601954/
https://ncbi.nlm.nih.gov/pubmed/23526887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001407
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