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Potential utility of aquaporin modulators for therapy of brain disorders
Of the several aquaporin (AQP) water channels expressed in the central nervous system, AQP4 is an attractive target for drug discovery. AQP4 is expressed in astroglia, most strongly at the blood–brain and brain–cerebrospinal fluid barriers. Phenotype analysis of AQP4 knockout mice indicates the invo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601944/ https://ncbi.nlm.nih.gov/pubmed/18655912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0079-6123(08)00446-9 |
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