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Calcium Signaling by STIM and Orai: Intimate Coupling Details Revealed

STIM (stromal interaction molecule) and Orai, two recently identified protein families, mediate cellular Ca(2+) signals through a remarkably dynamic interaction. STIM proteins are sensors of Ca(2+) stored within the endoplasmic reticulum (ER). Orai proteins are highly selective plasma membrane (PM)...

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Bibliografische gegevens
Hoofdauteurs: Wang, Youjun, Deng, Xiaoxiang, Gill, Donald L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601893/
https://ncbi.nlm.nih.gov/pubmed/21081752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.3148pe42
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