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Calcium Signaling by STIM and Orai: Intimate Coupling Details Revealed
STIM (stromal interaction molecule) and Orai, two recently identified protein families, mediate cellular Ca(2+) signals through a remarkably dynamic interaction. STIM proteins are sensors of Ca(2+) stored within the endoplasmic reticulum (ER). Orai proteins are highly selective plasma membrane (PM)...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601893/ https://ncbi.nlm.nih.gov/pubmed/21081752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.3148pe42 |
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