STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation

STIM1 and CRACM1 (or Orai1) are essential molecular components mediating store-operated Ca(2+) entry (SOCE) and Ca(2+) release-activated Ca(2+) (CRAC) currents. Although STIM1 acts as a luminal Ca(2+) sensor in the endoplasmic reticulum (ER), the function of STIM2 remains unclear. Here we reveal tha...

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Bibliografiske detaljer
Main Authors: Parvez, Suhel, Beck, Andreas, Peinelt, Christine, Soboloff, Jonathan, Lis, Annette, Monteilh-Zoller, Mahealani, Gill, Donald. L., Fleig, Andrea, Penner, Reinhold
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601890/
https://ncbi.nlm.nih.gov/pubmed/17905723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.07-9449com
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