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Aminoacyl-tRNA Substrate and Enzyme Backbone Atoms Contribute to Translational Quality Control by YbaK

Amino acids are covalently attached to their corresponding tRNAs by aminoacyl-tRNA synthetases. Proofreading mechanisms exist to ensure that high fidelity is maintained in this key step in protein synthesis. Prolyl-tRNA synthetase (ProRS) can misacylate cognate tRNA(Pro) with Ala and Cys. The cis-ed...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kumar, Sandeep, Das, Mom, Hadad, Christopher M., Musier-Forsyth, Karin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601562/
https://ncbi.nlm.nih.gov/pubmed/23185990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp308628y
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