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Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae.

Translation intitiation factor eIF-5A (previously named eIF-4D) is a highly conserved protein that promotes formation of the first peptide bond. One of its lysine residues is modified by spermidine to form hypusine, a posttranslational modification unique to eIF-5A. To elucidate the function of eIF-...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Main Authors: Schnier, J, Schwelberger, H G, Smit-McBride, Z, Kang, H A, Hershey, J W
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1991
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360154/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1903841/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.6.3105
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