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(18)F-misonidazole PET imaging of hypoxia in micrometastases and macroscopic xenografts of human non-small cell lung cancer: a correlation with autoradiography and histological findings

The objective of this study was to determine whether (18)F-misonidazole could detect hypoxia in macroscopic and microscopic tumors in mice. In nude mice, subcutaneous xenografts and peritoneal metastases were generated utilizing human non-small cell lung cancer A549 and HTB177 cells. Animals were co...

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Detalhes bibliográficos
Main Authors: Huang, Tao, Civelek, A Cahid, Zheng, Huaiyu, Ng, Chin K, Duan, Xiaoxian, Li, Junling, Postel, Gregory C, Shen, Baozhong, Li, Xiao-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601474/
https://ncbi.nlm.nih.gov/pubmed/23526377
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