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The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor.

The W/c-kit and Steel loci respectively encode a receptor tyrosine kinase (Kit) and its extracellular ligand, Steel factor, which are essential for the development of hematopoietic, melanocyte, and germ cell lineages in the mouse. To determine the biochemical basis of the Steel/W developmental pathw...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rottapel, R, Reedijk, M, Williams, D E, Lyman, S D, Anderson, D M, Pawson, T, Bernstein, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1991
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC360141/
https://ncbi.nlm.nih.gov/pubmed/1710023
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