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SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat.

Mutations in the SPT5 gene of Saccharomyces cerevisiae were isolated previously as suppressors of delta insertion mutations at HIS4 and LYS2. In this study we have shown that spt5 mutations suppress the his4-912 delta and lys2-128 delta alleles by altering transcription. We cloned the SPT5 gene and...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Swanson, M S, Malone, E A, Winston, F
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360134/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1840633/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.6.3009
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