TIF4631 and TIF4632: two yeast genes encoding the high-molecular-weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif-like sequence and carry out an essential function.

The 5' ends of eukaryotic mRNAs are blocked by a cap structure, m7GpppX (where X is any nucleotide). The interaction of the cap structure with a cap-binding protein complex is required for efficient ribosome binding to the mRNA. In Saccharomyces cerevisiae, the cap-binding protein complex is a heter...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Goyer, C, Altmann, M, Lee, H S, Blanc, A, Deshmukh, M, Woolford, J L, Trachsel, H, Sonenberg, N
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1993
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360119/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8336723/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.8.4860-4874.1993
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