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Can immunotherapy specifically target acute myeloid leukemic stem cells?

Accumulating evidence supports the role of leukemic stem cells (LSCs) in the high relapse rate of acute myeloid leukemia (AML) patients. The clinical relevance of LSCs, which were originally characterized in xenograft models, has recently been confirmed by the finding that stem cell-like gene expres...

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Detalhes bibliográficos
Main Authors: Snauwaert, Sylvia, Vandekerckhove, Bart, Kerre, Tessa
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601163/
https://ncbi.nlm.nih.gov/pubmed/23526057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22943
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