Transcriptome and Biochemical Analysis Reveals That Suppression of GPI-Anchor Synthesis Leads to Autophagy and Possible Necroptosis in Aspergillus fumigatus

Previously, it has been shown that GPI proteins are required for cell wall synthesis and organization in Aspergillus fumigatus, a human opportunistic pathogen causing life-threatening invasive aspergillosis (IA) in immunocompromised patients. Blocking GPI anchor synthesis leads to severe phenotypes...

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Detalhes bibliográficos
Main Authors: Yan, Jianghong, Du, Ting, Zhao, Wan, Hartmann, Thomas, Lu, Hua, Lü, Yang, Ouyang, Haomiao, Jiang, Xuejun, Sun, Lei, Jin, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601126/
https://ncbi.nlm.nih.gov/pubmed/23527074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059013
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