Induction of RET Dependent and Independent Pro-Inflammatory Programs in Human Peripheral Blood Mononuclear Cells from Hirschsprung Patients

Hirschsprung disease (HSCR) is a rare congenital anomaly characterized by the absence of enteric ganglia in the distal intestinal tract. While classified as a multigenic disorder, the altered function of the RET tyrosine kinase receptor is responsible for the majority of the pathogenesis of HSCR. Re...

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Main Authors: Rusmini, Marta, Griseri, Paola, Lantieri, Francesca, Matera, Ivana, Hudspeth, Kelly L., Roberto, Alessandra, Mikulak, Joanna, Avanzini, Stefano, Rossi, Valentina, Mattioli, Girolamo, Jasonni, Vincenzo, Ravazzolo, Roberto, Pavan, William J., Pini-Prato, Alessio, Ceccherini, Isabella, Mavilio, Domenico
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601093/
https://ncbi.nlm.nih.gov/pubmed/23527089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059066
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