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A Single Disulfide Bond Disruption in the β3 Integrin Subunit Promotes Thiol/Disulfide Exchange, a Molecular Dynamics Study

The integrins are a family of membrane receptors that attach a cell to its surrounding and play a crucial function in cell signaling. The combination of internal and external stimuli alters a folded non-active state of these proteins to an extended active configuration. The β3 subunit of the platele...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Levin, Lihie, Zelzion, Ehud, Nachliel, Esther, Gutman, Menachem, Tsfadia, Yossi, Einav, Yulia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601072/
https://ncbi.nlm.nih.gov/pubmed/23527123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059175
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