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CSF-1R up-regulation is associated with response to pharmacotherapy targeting tyrosine kinase activity in AML cell lines

BACKGROUND: The oncogenic potential of colony stimulating factor 1 receptor (CSF-1R) has been well described, while its relevance for human acute myelogenous leukemia (AML) is still undetermined. In a recent clinical trial for AML, sunitinib was found to hold potential therapeutic benefit, however,...

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Autors principals: Kogan, Michael, Fischer-Smith, Tracy, Kaminsky, Rafal, Lehmicke, Gabrielle, Rappaport, Jay
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601026/
https://ncbi.nlm.nih.gov/pubmed/22399609
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