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Kupffer cell-mediated hepatic injury induced by silica nanoparticles in vitro and in vivo

Silica nanoparticles (SiO(2) NPs) have been shown to exert cytotoxic effects in hepato-cytes and to cause liver injury. In the liver, Kupffer cells (KCs), as the resident macrophages, play an important role in the normal physiology and homeostasis of the liver. Nevertheless, few studies have attempt...

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Detalhes bibliográficos
Main Authors: Chen, Qingqing, Xue, Yang, Sun, Jiao
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600997/
https://ncbi.nlm.nih.gov/pubmed/23515466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S42242
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