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Comparisons of Analysis Methods for Proof-of-Concept Trials

Drug development struggles with high costs and time consuming processes. Hence, a need for new strategies has been accentuated by many stakeholders in drug development. This study proposes the use of pharmacometric models to rationalize drug development. Two simulated examples, within the therapeuti...

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Bibliografiske detaljer
Main Authors: Karlsson, K E, Vong, C, Bergstrand, M, Jonsson, E N, Karlsson, M O
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600728/
https://ncbi.nlm.nih.gov/pubmed/23887593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2012.24
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