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The distal enhancer implicated in the developmental regulation of the tyrosine aminotransferase gene is bound by liver-specific and ubiquitous factors.

Tyrosine aminotransferase gene expression is confined to parenchymal cells of the liver, is inducible by glucocorticoids and glucagon, and is repressed by insulin. Three enhancers control this tissue-specific and hormone-dependent activity, one of which, located at -11 kb, is implicated in establish...

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Bibliografiska uppgifter
I publikationen:Mol Cell Biol
Huvudupphovsmän: Nitsch, D, Schütz, G
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 1993
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360060/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8101632/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.8.4494
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