Comprehensive profiling of circulating microRNA via small RNA sequencing of cDNA libraries reveals biomarker potential and limitations

We profiled microRNAs (miRNAs) in cell-free serum and plasma samples from human volunteers using deep sequencing of barcoded small RNA cDNA libraries. By introducing calibrator synthetic oligonucleotides during library preparation, we were able to calculate the total as well as specific concentratio...

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מידע ביבליוגרפי
Main Authors: Williams, Zev, Ben-Dov, Iddo Z., Elias, Rony, Mihailovic, Aleksandra, Brown, Miguel, Rosenwaks, Zev, Tuschl, Thomas
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2013
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600502/
https://ncbi.nlm.nih.gov/pubmed/23440203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214046110
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