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Asymmetric Chiral Ligand-Directed Alkene Dioxygenation

[Image: see text] A Pd-catalyzed asymmetric alkene 1,2-dioxygenation reaction is described. The diastereoselectivity of the reaction is controlled by tethering a chiral oxime ether directing group to the alkene substrate. The best selectivities are obtained with 8-substituted menthone-derived oxime...

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Autori principali: Neufeldt, Sharon R., Sanford, Melanie S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600423/
https://ncbi.nlm.nih.gov/pubmed/23249401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol303003g
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