Aberrant expression of LMO4 induces centrosome amplification and mitotic spindle abnormalities in breast cancer cells

The LIM-only protein, LMO4, is a transcriptional modulator overexpressed in breast cancer. It is oncogenic in murine mammary epithelium and required for G2/M progression of ErbB2-dependent cells as well as growth and invasion of other breast cancer cell types. However, the mechanisms underlying the...

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Autores principales: Montañez-Wiscovich, Marjorie E., Shelton, Melissa D., Seachrist, Darcie D., Lozada, Kristen L., Johnson, Emhonta J., Miedler, John D., Abdul-Karim, Fadi W., Visvader, Jane E., Keri, Ruth A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600378/
https://ncbi.nlm.nih.gov/pubmed/20814902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2762
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