Peptide antisera to human colony-stimulating factor 1 receptor detect ligand-induced conformational changes and a binding site for phosphatidylinositol 3-kinase.

A peptide antiserum (anti-A) directed to the intracellular, juxtamembrane region (residues 552 to 574) of the human colony-stimulating factor 1 receptor (CSF-1R) precipitated only ligand-activated, native receptors from solution but bound to unstimulated forms after their denaturation. Two peptide a...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Downing, J R, Shurtleff, S A, Sherr, C J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360016/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1708091/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.5.2489-2495.1991
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