Four of the seven zinc fingers of the Evi-1 myeloid-transforming gene are required for sequence-specific binding to GA(C/T)AAGA(T/C)AAGATAA.

Expression of the Evi-1 gene is activated in murine myeloid leukemias by retroviral insertions and in human acute myelogenous leukemia by translocations and inversions involving chromosome band 3q26 where the gene resides. Aberrant expression of the Evi-1 gene has been shown to interfere with myeloi...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Delwel, R, Funabiki, T, Kreider, B L, Morishita, K, Ihle, J N
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1993
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359982/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8321231/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.7.4291-4300.1993
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