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The scaffolding protein GRASP/Tamalin directly binds to Dock180 as well as to cytohesins facilitating GTPase crosstalk in epithelial cell migration

BACKGROUND: The transition of epithelial cells from their normal non-motile state to a motile one requires the coordinated action of a number of small GTPases. We have previously shown that epithelial cell migration is stimulated by the coordinated activation of Arf and Rac GTPases. This crosstalk d...

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Autors principals: Attar, Myriam A, Santy, Lorraine C
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599651/
https://ncbi.nlm.nih.gov/pubmed/23441967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-14-9
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