4-Aryl-4H-naphthopyrans derivatives: one-pot synthesis, evaluation of Src kinase inhibitory and anti-proliferative activities

BACKGROUND: A series of 2-amino-4-aryl-4H-benzo[h or f]chromene-3-carbonitrile derivatives were synthesized and evaluated for inhibition of Src kinase and cell proliferation in breast carcinoma (BT-20) cell lines. METHODS: The one-pot, three-component reaction of α or β-naphthol, malonitrile and an...

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Detalhes bibliográficos
Main Authors: Rafinejad, Ali, Fallah-Tafti, Asal, Tiwari, Rakesh, Shirazi, Amir Nasrolahi, Mandal, Deendayal, Shafiee, Abbas, Parang, Keykavous, Foroumadi, Alireza, Akbarzadeh, Tahmineh
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599540/
https://ncbi.nlm.nih.gov/pubmed/23351304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2008-2231-20-100
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