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Generalization of the normal-exponential model: exploration of a more accurate parametrisation for the signal distribution on Illumina BeadArrays

BACKGROUND: Illumina BeadArray technology includes non specific negative control features that allow a precise estimation of the background noise. As an alternative to the background subtraction proposed in BeadStudio which leads to an important loss of information by generating negative values, a b...

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Détails bibliographiques
Auteurs principaux: Plancade, Sandra, Rozenholc, Yves, Lund, Eiliv
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599453/
https://ncbi.nlm.nih.gov/pubmed/23231059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-329
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