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In vitro activation of a transcription factor by gamma interferon requires a membrane-associated tyrosine kinase and is mimicked by vanadate.

Gamma interferon (IFN-gamma) activates the formation of a DNA-binding protein complex (FcRF gamma) that recognizes the gamma response region (GRR) of the promoter for the human high-affinity Fc gamma receptor. In a membrane-enriched fraction prepared from human peripheral blood monocytes, IFN-gamma...

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Publicat a:Mol Cell Biol
Autors principals: Igarashi, K, David, M, Larner, A C, Finbloom, D S
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359945/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8321205/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.7.3984-3989.1993
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