High glucose induces apoptosis and suppresses proliferation of adult rat neural stem cells following in vitro ischemia

BACKGROUND: Post-stroke hyperglycemia appears to be associated with poor outcome from stroke, greater mortality, and reduced functional recovery. Focal cerebral ischemia data support that neural stem cells (NSCs) play an important role in post-ischemic repair. Here we sought to evaluate the negative...

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Main Authors: Chen, Jian, Guo, Yang, Cheng, Wei, Chen, Ruiqing, Liu, Tianzhu, Chen, Zhenzhou, Tan, Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599336/
https://ncbi.nlm.nih.gov/pubmed/23452440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-24
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