Elucidating the crosstalk mechanism between IFN-gamma and IL-6 via mathematical modelling

BACKGROUND: Interferon-gamma (IFN-gamma) and interleukin-6 (IL-6) are multifunctional cytokines that regulate immune responses, cell proliferation, and tumour development and progression, which frequently have functionally opposing roles. The cellular responses to both cytokines are activated via th...

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Detalhes bibliográficos
Main Authors: Qi, Yun-feng, Huang, Yan-xin, Wang, Hong-yan, Zhang, Yu, Bao, Yong-li, Sun, Lu-guo, Wu, Yin, Yu, Chun-lei, Song, Zhen-bo, Zheng, Li-hua, Sun, Ying, Wang, Guan-nan, Li, Yu-xin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599299/
https://ncbi.nlm.nih.gov/pubmed/23384097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-41
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