Exposure of RML scrapie agent to a sodium percarbonate-based product and sodium dodecyl sulfate renders PrP(Sc) protease sensitive but does not eliminate infectivity

BACKGROUND: Prions, the causative agents of the transmissible spongiform encephalopathies, are notoriously difficult to inactivate. Current decontamination recommendations by the World Health Organization include prolonged exposure to 1 N sodium hydroxide or > 20,000 ppm sodium hypochlorite, or a...

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Bibliographic Details
Main Authors: Smith, Jodi D, Nicholson, Eric M, Foster, Gregory H, Greenlee, Justin J
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599183/
https://ncbi.nlm.nih.gov/pubmed/23311930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-6148-9-8
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