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Exposure of RML scrapie agent to a sodium percarbonate-based product and sodium dodecyl sulfate renders PrP(Sc) protease sensitive but does not eliminate infectivity
BACKGROUND: Prions, the causative agents of the transmissible spongiform encephalopathies, are notoriously difficult to inactivate. Current decontamination recommendations by the World Health Organization include prolonged exposure to 1 N sodium hydroxide or > 20,000 ppm sodium hypochlorite, or a...
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Formato: | Artigo |
Idioma: | Inglês |
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BioMed Central
2013
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3599183/ https://ncbi.nlm.nih.gov/pubmed/23311930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-6148-9-8 |
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