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Visceral Endoderm Expression of Yin-Yang1 (YY1) Is Required for VEGFA Maintenance and Yolk Sac Development

Mouse embryos lacking the polycomb group gene member Yin-Yang1 (YY1) die during the peri-implantation stage. To assess the post-gastrulation role of YY1, a conditional knock-out (cKO) strategy was used to delete YY1 from the visceral endoderm of the yolk sac and the definitive endoderm of the embryo...

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Detalhes bibliográficos
Main Authors: Rhee, Siyeon, Guerrero-Zayas, Mara-Isel, Wallingford, Mary C., Ortiz-Pineda, Pablo, Mager, Jesse, Tremblay, Kimberly D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598950/
https://ncbi.nlm.nih.gov/pubmed/23554936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058828
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