The Interplay between Chondrocyte Redifferentiation Pellet Size and Oxygen Concentration

Chondrocytes dedifferentiate during ex vivo expansion on 2-dimensional surfaces. Aggregation of the expanded cells into 3-dimensional pellets, in the presence of induction factors, facilitates their redifferentiation and restoration of the chondrogenic phenotype. Typically 1×10(5)–5×10(5) chondrocyt...

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Detalhes bibliográficos
Main Authors: Babur, Betul Kul, Ghanavi, Parisa, Levett, Peter, Lott, William B., Klein, Travis, Cooper-White, Justin J., Crawford, Ross, Doran, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598946/
https://ncbi.nlm.nih.gov/pubmed/23554943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058865
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