Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines

G-quadruplexes are higher-order DNA structures formed from guanine-rich sequences, and have been identified as attractive anticancer drug targets. Elucidating the three-dimensional structure of G-quadruplex with 9-amino acridines and the specific interactions involved in binding selectivity are the...

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Main Authors: Ferreira, Ruben, Artali, Roberto, Benoit, Adam, Gargallo, Raimundo, Eritja, Ramon, Ferguson, David M., Sham, Yuk Y., Mazzini, Stefania
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598906/
https://ncbi.nlm.nih.gov/pubmed/23554865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057701
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