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Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines
G-quadruplexes are higher-order DNA structures formed from guanine-rich sequences, and have been identified as attractive anticancer drug targets. Elucidating the three-dimensional structure of G-quadruplex with 9-amino acridines and the specific interactions involved in binding selectivity are the...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3598906/ https://ncbi.nlm.nih.gov/pubmed/23554865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057701 |
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