The Role of Systematic Reviews in Pharmacovigilance Planning and Clinical Trials Authorisation Application: Example from the SLEEPS Trial

BACKGROUND: Adequate sedation is crucial to the management of children requiring assisted ventilation on Paediatric Intensive Care Units (PICU). The evidence-base of randomised controlled trials (RCTs) in this area is small and a trial was planned to compare midazolam and clonidine, two sedatives wi...

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Bibliografiske detaljer
Main Authors: Gamble, Carrol, Wolf, Andrew, Sinha, Ian, Spowart, Catherine, Williamson, Paula
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598865/
https://ncbi.nlm.nih.gov/pubmed/23554852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051787
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