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Improving stability and understandability of genotype-phenotype mapping in Saccharomyces using regularized variable selection in L-PLS regression

BACKGROUND: Multivariate approaches have been successfully applied to genome wide association studies. Recently, a Partial Least Squares (PLS) based approach was introduced for mapping yeast genotype-phenotype relations, where background information such as gene function classification, gene dispens...

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Hlavní autoři: Mehmood, Tahir, Warringer, Jonas, Snipen, Lars, Sæbø, Solve
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598729/
https://ncbi.nlm.nih.gov/pubmed/23216988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-327
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