Immunization with Recombinant Prion Protein Leads to Partial Protection in a Murine Model of TSEs through a Novel Mechanism

Transmissible spongiform encephalopathies are neurodegenerative diseases, which despite fervent research remain incurable. Immunization approaches have shown great potential at providing protection, however tolerance effects hamper active immunization protocols. In this study we evaluated the antige...

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Main Authors: Xanthopoulos, Konstantinos, Lagoudaki, Rosa, Kontana, Anastasia, Kyratsous, Christos, Panagiotidis, Christos, Grigoriadis, Nikolaos, Yiangou, Minas, Sklaviadis, Theodoros
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598700/
https://ncbi.nlm.nih.gov/pubmed/23554984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059143
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