Immunization with Recombinant Prion Protein Leads to Partial Protection in a Murine Model of TSEs through a Novel Mechanism

Transmissible spongiform encephalopathies are neurodegenerative diseases, which despite fervent research remain incurable. Immunization approaches have shown great potential at providing protection, however tolerance effects hamper active immunization protocols. In this study we evaluated the antige...

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Detalhes bibliográficos
Main Authors: Xanthopoulos, Konstantinos, Lagoudaki, Rosa, Kontana, Anastasia, Kyratsous, Christos, Panagiotidis, Christos, Grigoriadis, Nikolaos, Yiangou, Minas, Sklaviadis, Theodoros
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598700/
https://ncbi.nlm.nih.gov/pubmed/23554984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059143
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